Cholesterol

Cholesterol

Symptoms

Diagnosis

Management

Prevention

What to Expect

Living Well

Cholesterol is a waxy substance your body needs to build healthy cells, but too much can create problems. When you have high cholesterol, fatty deposits can build up in your blood vessels, making it harder for blood to flow through your arteries. This increases your risk of heart attack and stroke.

Many people with high cholesterol don’t have symptoms, which is why it’s often called a “silent” condition. Regular testing helps you know your numbers and take steps to keep them in a healthy range.

With the right approach, most people can successfully manage their cholesterol levels and reduce their risk of serious health problems.

Cholesterol travels through your bloodstream in tiny packages called lipoproteins. Your body makes all the cholesterol it needs, but you also get cholesterol from foods — especially animal products like meat, eggs, and dairy.

Types of cholesterol:

  • LDL (“bad”) cholesterol — carries cholesterol to your arteries, where it can build up and form blockages

  • HDL (“good”) cholesterol — carries cholesterol away from arteries to your liver for removal

High cholesterol affects about 38% of American adults. It can occur at any age and usually develops silently over time, which is why screening is essential.

When cholesterol stays high, fatty deposits called plaque form in arteries (atherosclerosis). This narrows arteries, reduces blood flow, and raises your risk of heart attack and stroke.

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Symptoms and Causes

High cholesterol rarely causes symptoms until it leads to complications. Most people learn they have it through a blood test.

In rare, severe cases, yellowish deposits called xanthomas can appear on the skin or around the eyes.

Factors that can raise cholesterol:

  • Diet high in saturated or trans fats (red meat, butter, fried foods)

  • Lack of physical activity (lowers HDL)

  • Smoking (damages vessels and reduces HDL)

  • Excess weight (especially around the waist)

  • Age and gender (risk rises with age; post-menopausal women face increased risk)

Other causes include:

  • Genetics — familial hypercholesterolemia causes very high LDL from birth

  • Medical conditions — diabetes, hypothyroidism, kidney disease

  • Medications — certain drugs may elevate cholesterol

Discuss your full health history and medications with your doctor to uncover contributing factors.

Diagnosis

A lipid panel (blood test) measures your cholesterol levels and helps your doctor evaluate heart-disease risk.

Usually, you’ll fast for 9–12 hours before testing. The lipid panel measures:

  • Total cholesterol — overall amount in your blood

  • LDL cholesterol — “bad” cholesterol

  • HDL cholesterol — “good” cholesterol

  • Triglycerides — another form of fat

Healthy adults should test every 4–6 years starting at age 20 — more often if you have risk factors (family history, diabetes, hypertension).

Your provider will assess your entire risk profile, not just one number, when planning your treatment.

Management and Treatment

Managing cholesterol begins with lifestyle adjustments, often enough for mild to moderate cases.

Lifestyle foundations

  • Heart-healthy diet — fruits, vegetables, whole grains, lean protein, and healthy fats

  • Physical activity — at least 150 minutes of moderate exercise weekly

  • Weight management — losing 5–10 pounds can improve cholesterol

  • Quit smoking — raises HDL and protects arteries

Medications

If lifestyle changes aren’t enough, your doctor may prescribe:

  • Statins (simvastatin, atorvastatin, rosuvastatin) — most common and well-researched

  • Ezetimibe — lowers cholesterol absorption in the intestines

  • PCSK9 inhibitors — powerful injectable options for high-risk patients

  • Bile acid sequestrants — bind cholesterol in the gut

Your treatment plan will be personalized to your risk, lab results, and overall health. Regular monitoring ensures you stay on target.

Prevention

Preventing high cholesterol — or keeping it from worsening — depends on consistent heart-healthy habits.

Nutrition tips:

  • Eat more plants and fiber-rich foods

  • Choose fish, poultry, and beans over red meat

  • Use olive or canola oil instead of butter

  • Avoid processed snacks and fried foods

Exercise & lifestyle:

  • Engage in daily movement (walking, swimming, cycling)

  • Maintain a healthy weight

  • Manage stress through yoga, breathing, or mindfulness

  • Limit alcohol and avoid tobacco

Family history:

If high cholesterol runs in your family, regular screening and proactive habits are even more important.

Outlook

The outlook for high cholesterol is excellent when managed early and consistently.

  • Lifestyle changes can lower LDL by 20–30%

  • Statins can lower LDL by 30–50% or more

  • Lower cholesterol = lower risk: up to 30% fewer heart attacks and 20% fewer strokes

Your long-term results depend on:

  • Early diagnosis and consistent management

  • Adherence to medications and lifestyle plans

  • Management of related conditions (e.g., diabetes, hypertension)

Most people see measurable improvements in 6–8 weeks and maintain healthy levels long-term with regular follow-up.

Living With High Cholesterol

Living with high cholesterol means making sustainable heart-healthy choices — not short-term fixes.

Practical daily steps:

  • Plan balanced meals ahead of time

  • Read nutrition labels for saturated/trans fats

  • Stay active doing things you enjoy

  • Use reminders for medications or appointments

Stay in touch with your healthcare team:

  • Report any side effects or new symptoms

  • Discuss challenges in maintaining your plan

  • Schedule check-ups and blood tests regularly

Managing cholesterol is a lifelong commitment — focus on progress and consistency.

Take Control of Your Heart Health

Ready to learn more about managing your cardiovascular health? Explore our comprehensive library of heart and vascular health resources.

References

American Heart Association. (2023). Cholesterol Management Guide. heart.org

Centers for Disease Control and Prevention. (2023). High Cholesterol Facts. cdc.gov

National Heart, Lung, and Blood Institute. (2022). High Blood Cholesterol: What You Need to Know. NIH Publication No. 22-HL-3280.

Grundy, S. M., et al. (2019). 2018 AHA/ACC Guideline on the Management of Blood Cholesterol. J Am Coll Cardiol, 73(24): e285–e350.

Mayo Clinic. (2023). High Cholesterol – Diagnosis and Treatment. mayoclinic.org