The 5th Right Heart Symposium Enduring

This program is no longer being offered with credits as it has expired.


The syndrome of right heart failure is poorly understood and defined. Clinicians often fail to diagnose early stages of the disease and allow the manifestations to progress to severe disability. There is a pressing need to define, understand, and inculcate awareness about this disease in clinicians. Similarly, understanding right heart dysfunction requires focused investigations and research study, best brought forth by a multidisciplinary collaboration. This program is intended for clinical and research professionals who are involved in the care of patients with, and the study of, right heart disease, congenital heart disease, pulmonary hypertension, and associated disorders.

The content of this internet enduring material activity was originally presented as part of a live event. It is divided into three different learning activities, each with multiple videos. For each of the three activities, learners must view all videos in their entirety and complete a post-activity assessment and evaluation before they are eligible for continuing credit. 


This program has been designed for physicians, pharmacists, hospitalists, surgeons, nurses, nurse practitioners, physician assistants, and allied healthcare professionals in the fields of cardiology, pulmonology, critical care medicine, emergency medicine, rheumatology, internal medicine, and vascular medicine.


By the end of the session the participant will be able to:

  • Describe the unique structure and function of the right ventricle (RV) with a focus on anatomical and embryological differences between the RV and LV
  • Discuss the importance of RV and pulmonary arterial coupling and its role in RV function and RV failure
  • Summarize the emerging role of advanced imaging in assessing RV function
  • Evaluate the current data regarding myocardial metabolism and RV function
  • Given a patient case, formulate a management approach that takes into account RV structure, function, and maladaptation


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of ScientiaCME and NATF. ScientiaCME is accredited by the ACCME to provide continuing medical education for physicians.

Physicians: ScientiaCME designates these internet enduring material activities for a maximum of 13 AMA PRA Category 1 Credit(s)™ toward the AMA Physician’s Recognition Award. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Nurse Practitioners (NPs): The American Academy of Nurse Practitioners accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME.  ScientiaCME will provide NPs who successfully complete each activity with a certificate of participation indicating that the activity was designated for AMA PRA Category 1 Credit(s)™.

Physician Assistants: The American Academy of Physician Assistants accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME.

Pharmacists: ScientiaCME is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. ScientiaCME designates the following CTEPH modules for a maximum of 13 contact hour(s) (1.30 CEUs). Proof of participation will be posted to your NABP CPE profile within 4 to 6 weeks to participants who have successfully completed the post-test.   Participants must participate in the entire group of presentations and complete the course evaluation to receive continuing pharmacy education credit. The modules are listed as follows:

  • 5th Right Heart Symposium, Part 1: 0574-9999-22-013-H01-P: 2.25 contact hours (0.225 CEUs)
  • 5th Right Heart Symposium, Part 2: 0574-9999-22-014-H01-P: 3.25 contact hours (0.325 CEUs)
  • 5th Right Heart Symposium, Part 3: 0574-9999-22-015-H01-P: 3.75 contact hours (0.375 CEUs)
  • 5th Right Heart Symposium, Part 4: 0574-9999-22-016-H01-P: 3.75 contact hours (0.375 CEUs)

This is an Knowledge (K)-type activity.

You must enter your NABP # and birth date correctly so that proof of participation can be posted to your NABP CPE profile. It is the learner’s responsibility to provide this information completely and accurately at the completion of the activity. Without providing it, the learner will NOT receive CPE credit for this activity.

The CPE statements of credit contain information provided to NABP from the Accreditation Council for Pharmacy Education (ACPE) via CPE Monitor®. ACPE policy states paper and/or electronic statements of credit may no longer be distributed directly to learners as proof of ACPE credit. The official record of credit may be located in the learner’s e-profile in CPE Monitor®

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 13 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Supported by educational grants from Acceleron, Actelion Pharmaceuticals US, Inc., a Janssen Pharmaceutical Company of Johnson & Johnson, and United Therapeutics. This internet enduring material activity is part of a series of activities.

Participation in these activities is free.

RELEASE DATE: May 4, 2022 — EXPIRATION DATE: May 3, 2023


The 5th Right Heart Symposium, Part 1

VIDEO 1: Right Ventricular Structure Function Relationship
Right Ventricular Contraction and Contractility
Tammo Delhaas, MD, PhD – Maastricht University

The Tricuspid Valve: The Foundation of Coupling
Andrew Peacock, Phil, MD, FRCP – University of Glasgow
VIDEO 2: Right Ventricular Structure Function Relationship
Tricuspid Valve Dysfunction: Current State of the Art and Future Prospects 
Rebecca T. Hahn, MD, FACC, FASE – Columbia University

Tricuspid Regurgitation: Consequences with a Price
Elizabeth Gay, MD – Harvard Medical School

Panel Discussion

5th Right Heart Symposium, Part 2

VIDEO 3: Assessment of the Right Heart: Integrative Approaches to Uncovering Right Heart Function
Dynamic Assessment of Right Ventricle-Pulmonary Artery Coupling: Application of Invasive CPET
David M. Systrom, MD – Harvard Medical School

Right Ventricular Load and Function: Assessing the Impact of Left Heart Function on the Right Side
Luke Howard, MA, Phil, FRCP – National Heart & Lung Institute, Imperial College London
VIDEO 4: Assessment of the Right Heart: Integrative Approaches to Uncovering Right Heart Function
Imaging Approaches to the Right Heart: Echo vs. cMR
Anne Marie Valente, MD – Harvard Medical School

Assessing RV Remodeling with PET in Patients with Pulmonary Hypertension
Marcelo Fernando Di Carli, MD – Harvard Medical School

Panel Discussion
VIDEO 5: Keynote Lecture
The Complex Relationship of the Right and Left Ventricle and Meaning of Ventricular Independence
Mandeep R. Mehra, MD, MSc, FRCP – Harvard Medical School

5th Right Heart Symposium, Part 3

VIDEO 6: Pulmonary Heart Disease and Remodeling
How Does Pulmonary Disease Drive Pulmonary Vascular and Myocardial Remodeling?
Paul Hassoun, MD – The Johns Hopkins University

How Does Left Heart Disease Drive Pulmonary Vascular and Right Ventricular Remodeling?
Stephan Rosenkranz, MD – University of Cologne

How Does Congenital Heart Disease Drive Pulmonary Vascular Remodeling?
Mary Mullen, MD, PhD – Harvard Medical School
VIDEO 7: Pulmonary Heart Disease and Remodeling
Right Heart Disease in the Absence of Pulmonary or Left Heart Disease
Michael M. Givertz, MD – Harvard Medical School

Molecular Phenotyping of the Right Heart System: Is the Fog Starting to Clear?
Jane Leopold, MD, FACC, FAHA, FSCAI – Harvard Medical School

Panel Discussion
VIDEO 8: Interventional Approaches to the Failing Right Heart
ECMO as a Bridge
Paul Heerdt, MD – Yale School of Medicine, New Haven, C

Chronic Thromboembolic Pulmonary Hypertension: Surgical, Medical, and Interventional Options for Treatment
Piotr Sobieszczyk, MD – Harvard Medical School

Percutaneous Approaches to RV Support Now and in the Future
Steven P. Keller, MD – Johns Hopkins Medicine

Panel Discussion

5th Right Heart Symposium, Part 4

VIDEO 9: Venous Thromboembolism
Submassive PE: What is it Really and What is the Best Approach to Treatment?
Gregory Piazza, MD, MS – Harvard Medical School

Acute PE and Impact on RV
Yolanda Bryce, MD – Weill Medical College of Cornell University

Massive and Catastrophic PE: Strategies for Circulatory Support Both Pharmacologically and Mechanically
David M. Dudzinski, MD, FAHA, FACC, FASE – Harvard Medical School

Panel Discussion
VIDEO 10: Keynote Lecture
Effects of Exercise Training on the Right Heart
Mary Beth Brown, PT, PhD – University of Washington
VIDEO 11: Critical Care and the Failing Right Heart
Drips to Machines – Supporting the Failing RH
Evelyn M. Horn, MD – Weill Cornell Medical College of Cornell University

Physiologic Impact of Mechanical Ventilation on the Right Heart
Inderjit Singh, MD – Yale University

Panel Discussion

Closing Remarks


Aaron Waxman, MD, PhD: Researcher, United Therapeutics

Andrew Peacock, Phil, MD: Advisory Board – Ferrer

Bradley A. Maron, MD: Steering Committee Member – Actelion; Investigator – Sponsored Research, Deerfield Corporation

Bradley Wertheim: Consultant – Change Healthcare

Evelyn Horn, MD: Data Safety Monitoring Board – AADi, SoniVie; Clinical Endpoint Committee – V-wave, Ltd.

Gregory Piazza, MD, MS: Research Grant – BMS/Pfizer, Janssen, Bayer, Portola, Amgen, Boston Scientific

Jane A Leopold, MD: Research Funding – Aria CV, Astellas, Inc.; Consultant – Abbott Vascular; Speaker – United Therapeutics

Luke Howard, MA, Phil: Advisor – Janssen, MSD, Bayer, Gossamer Bio; Speaker – Janssen, MSD, Bayer; Research Grants – Janssen

Mandeep R. Mehra, MD: Consultant – Abbott, Bayer, Portola, Mesoblast, NuPulse, Medtronic, FineHeart, Janssen, Triple Gene, Roivant, Baim Institute for Clinical Research, Leviticus

Marcelo F. Di Carli, MD: Research Grant – Gilead Sciences, Spectrum Dynamics

Paul Hassoun, MD: Consultant – MS&D

Paul Heerdt, MD: Consultant – Philips, BaudaxBio, Baxter

Phillip Joseph, MD: Consultant – United Therapeutics

Rebecca Hahn, MD: Consultant – Abbott Vascular, Boston Scientific Corp., Edwards Lifescience, Medtronic

Stephan Rosenkranz, MD: Consultant – Abbott, Acceleron, Actelion, Bayer, Janssen, MSD, Novartis, United Therapeutics, Vifor; Research Grants – Actelion, AstraZeneca, Bayer, Novartis, Janssen; Speaker – Actelion, Bayer, BMS, Ferrer, Janssen, MSD, Novartis, Pfizer, United Therapeutics, Vifor

Steven Keller, MD: Consultant – Abiomed, Inc., X-COR Therapeutics, Inc., CBSET, Inc.; Advisor – Paragonix Technologies

Individuals with no conflicts of interest to disclose: 

  • Content reviewer: Charles J Turck, PharmD, BCPS, BCCCP, President, ScientiaCME
  • Anne Marie Valente, MD
  • David Dudzinski, MD
  • David Systrom, MD
  • Eileen Harder, MD
  • Elizabeth Gay, MD
  • Inderjit Singh, MD
  • Katharine Clapham, MD
  • Mary Beth Brown, PT, PhD
  • Mary Mullen, MD, PhD
  • Michael Givertz, MD
  • Piotr Sobieszczyk, MD
  • Tammo Delhaas, MD
  • Yolanda Bryce, MD


  • Read the learning objectives above.
  • Take the Pre-Test (optional). Completion of the pre-test will help us evaluate the knowledge gained by participating in this CME activity.
  • View the online activity. You may view this in more than one session, and may pause or repeat any portion of the presentation if you need to.
  • Take the post-test.
  • Complete the activity evaluation and CME registration. A CE certificate will be emailed to you immediately. 



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